ChemicalBook > CAS DataBase List > (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
- Product Name
- (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
- CAS No.
- 170847-18-4
- Chemical Name
- (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID
- Synonyms
- rac-APICA;(RS)-APICA;(RS) APICA,(RS)APICA;(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID;1H-Indene-1-carboxylic acid, 1-amino-2,3-dihydro-5-phosphono-
- CBNumber
- CB0299684
- Molecular Formula
- C10H12NO5P
- Formula Weight
- 257.18
- MOL File
- Mol file
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(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID Property
- Boiling point:
- 559.9±60.0 °C(Predicted)
- Density
- 1?+-.0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- Soluble to 100 mM in 1.1eq. NaOH
- form
- Powder
- pka
- 1.34±0.40(Predicted)
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N-Bromosuccinimide Price
Tocris
- Product number
- 1073
- Product name
- (RS)-APICA
- Packaging
- 10
- Price
- $168
- Updated
- 2021/12/16
TRC
- Product number
- A609148
- Product name
- rac-APICA
- Packaging
- 25mg
- Price
- $240
- Updated
- 2021/12/16
TRC
- Product number
- A609148
- Product name
- rac-APICA
- Packaging
- 10mg
- Price
- $120
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6584
- Product name
- (RS)-APICA
- Packaging
- 10mg
- Price
- $251
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CCH0006416
- Product name
- (RS)-APICA
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $685.21
- Updated
- 2021/12/16
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(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
(RS)-APICA is a group II metabotropic glutamate receptor antagonist.
Biological Activity
The rigidified analog of MPPG ((RS)-a-Methyl-4-phosphonophenylglycine ); a selective group II metabotropic glutamate receptor antagonist (IC 50 = 30 μ M) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses an unusual inverse agonist-like action.
(RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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